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NAMs
open-access
NAMs and acute systemic toxicity
The paper discusses the global regulatory requirements for assessing the systemic toxicity of chemicals through various exposure routes (oral, dermal, and inhalation) for human health risk assessment. It focuses on the efforts of the International Cooperation on Alternative Test Methods (ICATM) to identify opportunities for using non-animal replacements for these tests.
QSAR
read-across
open-access
paper
Innovative solutions for enhancing chemical safety assessment
Both papers present a way to address one of the major challenge of chemical safety assessment that is the sheer scale of the assessment exercise: a new classification scheme designed to lead to the same levels of protection, without necessarily aiming to predict adverse effects in animal studies. The new classification scheme will rank chemicals into three levels of concern (high, medium and low) based on toxicodynamic (TD) and toxicokinetic (TK) considerations.
QSAR
read-across
New Release of "NAMs - Use and Application of QSAR and Read-Across" Training Course
QSAR
read-across
Save the Date for the Upgraded Version of Our Training Course
QSAR
read-across
New OECD QSAR Toolbox version available
paper
read-across
open-access
endocrine
NAMs
A KNIME Workflow to Assist the Analogue Identification for Read-Across, Applied to Aromatase Activity
cosmetics
IATA
NAMs
Master class: Animal-free Safety Assessment for Cosmetics
NAMs
cosmetics
Fragrance Materials Safety Assessment Database
NAMs
endocrine
EPA - Availability of New Approach Methodologies (NAMs) in the Endocrine Disruptor Screening Program (EDSP)
NAMs
open-access
read-across
food
QSAR
Implementing NAMs in food safety assessments: Strategic objectives and actions taken by EFSA
read-across
open-access
paper
Quantifying Analogue Suitability for SAR-Based Read-Across Toxicological Assessment
open-access
NAMs
read-across
VERA: A New Open-Access Software
NAMs
OECD-series
IATA
video-recording
OECD IATA Case Studies Project: video available
NAMs
tobacco-products
open-access
Symposium Explores Application of NAMs to Tobacco Products
A new publication reports on a 2021 symposium that explored the use of new approach methodologies for regulatory decision making for tobacco products.
webinar
29 Nov - In Silico / Mechanistic and Discovery Toxicology speciality sections’ joint workshop: hands-on modelling of safety data for non-experts
skin-sensitization
video-recording
How to resolve inconclusive predictions from defined approaches for skin sensitisation in OECD Guideline No. 497
NAMs
video-recording
Frameworks for establishing scientific confidence in new approach methodologies
NAMs
video-recording
Recordings now available for "Clustering and Classification Workshop"
titolo
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